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Originally Posted by Georgiana  Secretion of glucagon (i.e. liberation of fat from fat cells) has little to do with the reading on the ketostix. To understand what ketostix tell you, you first need to understand how ketone bodies are formed and used................. |
Great post. Just one correction: Acetyl-CoA is used as substrate for making ketone bodies not because of a lack of oxygen, but because oxaloacetate is required for acetyl-coa to proceed normally through the TCA cycle. During periods of low carbohydrate intake, oxaloacetate is shunted away from the TCA cycle so its carbon skeleton can be used for gluconeogenesis; the liver then produces kb's as an alternative method for dealing with excess acetyl-coa.