Kristen, some people see an initial cholesterol increase in the first few months, but as the weight comes off and your blood sugar stabilizes at a much lower level, many people see a significant drop in cholesterol. I am one of them. I credit exercise the most, but the Atkins diet definitely plays its part too. My cholesterol was never sky high--189, but now it is 149 and the good one is high and the bad one is low. Can't ask for more than that.