The finding suggests the muscle has a metabolic "memory" of obesity, and it may explain why obese people have such a hard time losing weight, even when they cut calories.
The study in the October issue of
Cell Metabolism also suggests that exercise may be able to override this programming and improve the ability of the obese to shed unwanted pounds.
Researchers found that the fat-building enzyme stearoyl-CoA desaturase-1 (SCD-1) is three times more abundant in the muscle of obese people than the muscle of lean people. This finding provides insight into an important link between obesity, diabetes and abnormal fat buildup in muscle, the researchers said.
[read the rest of the article at the link below]
http://health.discovery.com/news/hea...y=29&year=2005
From DiscoveryChannel.com
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December 21st, 2005, 01:50 PM
Obesity Linked to Fat Gain in Muscles 
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